Association of TREX1 polymorphism
Association of TREX1 polymorphism with disease progression in human immunodeficiency virus type-1 (HIV-1) infected patients
The time interval between HIV-1 infection and AIDS development is not the same in all patients and depends largely on the genetic background of the individual. Polymorphisms in the TREX1 gene, the main enzyme in the clearance of cytosolic DNA, affect type 1 interferon-mediated inflammatory response in HIV-1 infection. We aimed to study the role of a single nucleotide polymorphism (rs3135941) of the TREX1 gene and the rate of disease progression in patients infected with HIV-1. A total of 190 HIV-1...
مشخصات مقاله ۳۸۶۴۱۶۲۹
| Title: | Association of TREX1 polymorphism with disease progression in human immunodeficiency virus type-1 (HIV-1) infected patients |
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استنادات
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| Author(s): | Tohidi, N., Manshadi, S.A.D., Hajiabdolbaghi, M. | |
| Published/Type: | 2023 (2023-12-1) / Original Article | |
| Journal: | Virus Genes, 59(6), pp. 831-835 | |
| Abstract:
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The time interval between HIV-1 infection and AIDS development is not the same in all patients and depends largely on the genetic background of the individual. Polymorphisms in the TREX1 gene, the main enzyme in the clearance of cytosolic DNA, affect type 1 interferon-mediated inflammatory response in HIV-1 infection. We aimed to study the role of a single nucleotide polymorphism (rs3135941) of the TREX1 gene and the rate of disease progression in patients infected with HIV-1. A total of 190 HIV-1... | |
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| View at: | Scopus PubMed | |
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